Modern aspects of equine rhinopneumonitis (literature review)
Abstract
Rhinopneumonitis is one of the most dangerous viral diseases of horses. It is spread across all continents of the globe and causes significant economic losses in the equine industry as a result of the reduced performance qualities of animals, abortions, and the birth of non-viable young animals (Oladunni, Horohov, & Chambers, 2019; Ataseven, Dağalp, Güzel, Başaran, Tan, & Geraghty, 2009; Bell et al., 2006; Castro, & Arbiza, 2017; Dunowska 2014; Dunowska et al., 2015; Sloet van Oldruitenborgh-Oosterbaan, Schipper, Goehring, & Gremmels, 1999; Diallo et al., 2008; Barbić et al., 2012; Schulman, Becker, van der Merwe, Guthrie, & Stout, 2015). Horse disease with rhinopneumonitis has recently become widespread in some regions of Ukraine (Halatiuk, Behas, Kanovskyi, Radzixovs`kij, & Ribachuk, 2008; Halatiuk, Kalnaus, Rublenko, & Yeroshenko, 2017). The work aimed to analyze professional literature sources, including electronic resources, regarding the contemporary aspects of the etiology, distribution, clinical manifestation, diagnosis, and prevention of equine rhinopneumonitis in different countries of the world. An analysis of professional literary sources published during 1991-2020 showed that the spread of rhinopneumonitis in most countries, including Ukraine is a significant threat to the equine industry (Ma, Azab, & Osterrieder, 2013; Taouji et al., 2002; Yildirim, Yilmaz, & Kirmizigul, 2015; Stasiak, Dunowska, Hills, & Rola, 2017; Oladunni, Horohov, & Chambers, 2019; Halatiuk, Behas, Kanovskyi, Radzixovs`kij, & Ribachuk, 2008). It is necessary to monitor the spread of the disease, especially during the latent course of the disease in the territory of our country taking into account the presence of different climatic zones and technological features of keeping and operating horses. Questions remain relevant concerning the development of effective means of immunoprophylaxis and treatment of horses with rhinopneumonitis (Schnabel et al., 2018; Oladunni, Horohov, & Chambers, 2019; Van der Meulen, Favoreel, Pensaert, & Nauwynck, 2006; Halatiuk, Behas, Kanovskyi, Radzixovs`kij, & Ribachuk, 2008).
Downloads
References
Allen, G. (2002). Respiratory infections by equine herpesvirus types 1 and 4. In P. Lekeux (Ed.), Equine Respiratory Diseases. Ithaca, NY: International Veterinary Information Service.
Allen, G., Kydd, J., Slater, J., & Smith, K. (2004). Equid herpesvirus 1 and equid herpesvirus 4 infections. Infect. Dis. Livest. 2, 829–859.
Ataseven, V. S., Dağalp, S. B., Güzel, M., Başaran, Z., Tan, M. T., & Geraghty, B. (2009). Prevalence of equine herpesvirus-1 and equine herpesvirus-4 infections in equidae species in Turkey as determined by ELISA and multiplex nested PCR. Research in veterinary science, 86(2), 339–344. DOI: 10.1016/j.rvsc.2008.06.001
Azab, W., Bedair, S., Abdelgawad, A., Eschke, K., Farag, G. K., Abdel-Raheim, A., Greenwood, A. D., Osterrieder, N., & Ali, A. (2019). Detection of equid herpesviruses among different Arabian horse populations in Egypt. Veterinary medicine and science, 5(3), 361–371. DOI: 10.1002/vms3.176
Barbić, L., Lojkić, I., Stevanović, V., Bedeković, T., Starešina, V., Lemo, N., Lojkić, M., & Madić, J. (2012). Two outbreaks of neuropathogenic equine herpesvirus type 1 with breed-dependent clinical signs. The Veterinary record, 170(9), 227. DOI: 10.1136/vr.100150
Bell, S. A., Balasuriya, U. B., Gardner, I. A., Barry, P. A., Wilson, W. D., Ferraro, G. L., & MacLachlan, N. J. (2006). Temporal detection of equine herpesvirus infections of a cohort of mares and their foals. Veterinary microbiology, 116(4), 249–257. DOI: 10.1016/j.vetmic.2006.05.002
Castro, E. R., & Arbiza, J. (2017). Detection and genotyping of equid herpesvirus 1 in Uruguay. Revue scientifique et technique (International Office of Epizootics), 36(3), 799–806. DOI: 10.20506/rst.36.3.2715
Damiani, A. M., de Vries, M., Reimers, G., Winkler, S., & Osterrieder, N. (2014). A severe equine herpesvirus type 1 (EHV-1) abortion outbreak caused by a neuropathogenic strain at a breeding farm in northern Germany. Veterinary microbiology, 172(3-4), 555–562. DOI: 10.1016/j.vetmic.2014.06.023
Del Piero, F., & Wilkins, P. A. (2001). Pulmonary vasculotropic EHV-1 infection in equids. Vet. Pathol. 38, 474.DOI: 10.1354/vp.38-4-474
Diallo, I. S., Hewitson, G. R., de Jong, A., Kelly, M. A., Wright, D. J., Corney, B. G., & Rodwell, B. J. (2008). Equine herpesvirus infections in yearlings in South-East Queensland. Archives of virology, 153(9), 1643–1649. DOI: 10.1007/s00705-008-0158-y
Dunowska, M. (2014). A review of equid herpesvirus 1 for the veterinary practitioner. Part A: clinical presentation, diagnosis and treatment. New Zealand veterinary journal, 62(4), 171–178. DOI: 10.1080/00480169.2014.899945
Dunowska, M. (2014). A review of equid herpesvirus 1 for the veterinary practitioner. Part B: pathogenesis and epidemiology. New Zealand veterinary journal, 62(4), 179–188. DOI: 10.1080/00480169.2014.899946
Dunowska, M., Gopakumar, G., Perrott, M. R., Kendall, A. T., Waropastrakul, S., Hartley, C. A., & Carslake, H. B. (2015). Virological and serological investigation of Equid herpesvirus 1 infection in New Zealand. Veterinary microbiology, 176(3-4), 219–228. DOI: 10.1016/j.vetmic.2015.01.016
Edington, N., Welch, H. M., & Griffiths, L. (1994). The prevalence of latent Equid herpesviruses in the tissues of 40 abattoir horses. Equine veterinary journal, 26(2), 140–142. DOI: 10.1111/j.2042-3306.1994.tb04353.x
Fritsche, A. K., & Borchers, K. (2011). Detection of neuropathogenic strains of Equid Herpesvirus 1 (EHV-1) associated with abortions in Germany. Veterinary microbiology, 147(1-2), 176–180. DOI: 10.1016/j.vetmic.2010.06.014
Garré, B., Van Der Meulen, K., Nugent, J., Neyts, J., Croubels, S., De Backer, P., & Nauwynck, H. (2007). In vitro susceptibility of six isolates of equine herpesvirus 1 to acyclovir, ganciclovir, cidofovir, adefovir, PMEDAP and foscarnet. Vet. Microbiol. 122, 43–51.
Garvey, M., Lyons, R., Hector, R. D., Walsh, C., Arkins, S., & Cullinane, A. (2019). Molecular Characterisation of Equine Herpesvirus 1 Isolates from Cases of Abortion, Respiratory and Neurological Disease in Ireland between 1990 and 2017. Pathogens (Basel, Switzerland), 8(1), 7. DOI: 10.3390/pathogens8010007
Gilkerson, J. R., Love, D. N., & Whalley, J. M. (1998). Epidemiology of equine herpesvirus abortion: searching for clues to the future. Australian veterinary journal, 76(10), 675–676. DOI: 10.1111/j.1751-0813.1998.tb12280.x
Halatiuk, O., Behas, V., Kanovskyi, A., Radzixovs`kij, M., & Ribachuk, Z. (2008). Epіzootolohіchnі osoblyvostі, lіkuvannia ta profіlaktyka rynopnevmonіi konei. Veterynarna medytsyna Ukrainy, 10, 14–16 [in Ukrainian].
Halatiuk, O., Behas, V., Kanovskyi, A., Radzixovs`kij, M., & Ribachuk, Z. (2008). Rynopnevmonіia konei : epіzootolohіia, lіkuvannia ta profіlaktyka. Zdorov'ia tvaryn і lіky, 10, 8–11 [in Ukrainian].
Halatiuk, O., Kalnaus, R., Rublenko, M., & Yeroshenko, O. (2017). Pokaznyky klіtynnoho metabolіzmu v syrovattsі konei za latentnoho perebіhu leptospіrozu ta rynopnevmonіi. Naukovyi vіsnyk LNUVMB іmenі S. Z. Hzhytskoho, 78(19), 18–22. DOI:10.1542/nvlvet7804
Karamendin, K., Ky`dy`rmanov, A., & Sayatov, M. (2013). Razrabotka PCzR test-sistemy` dlya odnovremennoj diagnostiki grippa i rinopnevmonii loshadej. Biotexnologiya. Teoriya i praktika, 1, 20–23. DOI: 10.11134/btp.1.2013.4
Koelle, D. M., Norberg, P., Fitzgibbon, M. P., Russell, R. M., Greninger, A. L., Huang, M. L., Stensland, L., Jing, L., Magaret, A. S., Diem, K., Selke, S., Xie, H., Celum, C., Lingappa, J. R., Jerome, K. R., Wald, A., & Johnston, C. (2017). Worldwide circulation of HSV-2 × HSV-1 recombinant strains. Scientific reports, 7, 44084. DOI: 10.1038/srep44084
Lang, A., de Vries, M., Feineis, S., Müller, E., Osterrieder, N., & Damiani, A. M. (2013). Development of a peptide ELISA for discrimination between serological responses to equine herpesvirus type 1 and 4. J. Virol. Methods 193, 667–673. DOI: 10.1016/j.jviromet.2013.07.044
Lunn, D., Davis-Poynter, N., Flaminio, M., Horohov, D., Osterrieder, K., Pusterla, N., & Townsend, H. (2009). Equine herpesvirus-1 consensus statement. J. Vet. Intern. Med. 23, 450–461. DOI: 10.1111/j.1939-1676.2009.0304.x
Ma, G., Azab, W., & Osterrieder, N. (2013). Equine herpesviruses type 1 (EHV-1) and 4 (EHV-4)--masters of co-evolution and a constant threat to equids and beyond. Veterinary microbiology, 167(1-2), 123–134. DOI:10.1016/j.vetmic.2013.06.018
Matczuk, A. K., Skarbek, M., Jackulak, N. A., & Bażanów, B. A. (2018). Molecular characterisation of equid alphaherpesvirus 1 strains isolated from aborted fetuses in Poland. Virology journal, 15(1), 186. DOI: 10.1186/s12985-018-1093-5
Maxwell, L. K., Bentz, B. G., Gilliam, L. L., Ritchey, J. W., Pusterla, N., Eberle, R., … Allen, G. (2017). Efficacy of the early administration of valacyclovir hydrochloride for the treatment of neuropathogenic equine herpesvirus type-1 infection in horses. Am. J. Vet. Res. 78, 1126–1139. DOI:10.2460/ajvr.78.10.1126
Mezhenskyi, A. (2013). Normatyvno-pravovі aspekty laboratornoi dіahnostyky zaraznykh khvorob konei v Ukrainі. Veterynarna medytsyna, 97, 198–200 [in Ukrainian]
Oladunni, F. S., Horohov, D. W., & Chambers, T. M. (2019). EHV-1: A Constant Threat to the Horse Industry. Frontiers in microbiology, 10, 2668. DOI:10.3389/fmicb.2019.02668
Pagamjav, O., Sakata, T., Matsumura, T., Yamaguchi, T., & Fukushi, H. (2005). Natural recombinant between equine herpesviruses 1 and 4 in the ICP4 gene. Microbiology and immunology, 49(2), 167–179. DOI: 10.1111/j.1348-0421.2005.tb03716.x
Paillot, R. (2020). Special Issue "Equine Viruses": Old "Friends" and New Foes?. Viruses, 12(2), 153. DOI: 10.3390/v12020153
Patel, J. R., & Heldens, J. (2005). Equine herpesviruses 1 (EHV-1) and 4 (EHV-4)--epidemiology, disease and immunoprophylaxis: a brief review. Veterinary journal (London, England : 1997), 170(1), 14–23. DOI: 10.1016/j.tvjl.2004.04.018
Pronost, S., Léon, A., Legrand, L., Fortier, C., Miszczak, F., Freymuth, F., & Fortier, G. (2010). Neuropathogenic and non-neuropathogenic variants of equine herpesvirus 1 in France. Veterinary microbiology, 145(3-4), 329–333. DOI:10.1016/j.vetmic.2010.03.031
Reed, S. M., & Toribio, R. E. (2004). Equine herpesvirus 1 and 4. The Veterinary clinics of North America. Equine practice, 20(3), 631–642. DOI: 10.1016/j.cveq.2004.09.001
Schnabel, C. L., Wimer, C. L., Perkins, G., Babasyan, S., Freer, H., Watts, C., Rollins, A., Osterrieder, N., & Wagner, B. (2018). Deletion of the ORF2 gene of the neuropathogenic equine herpesvirus type 1 strain Ab4 reduces virulence while maintaining strong immunogenicity. BMC veterinary research, 14(1), 245. DOI: 10.1186/s12917-018-1563-4
Schulman, M. L., Becker, A., van der Merwe, B. D., Guthrie, A. J., & Stout, T. A. (2015). Epidemiology and reproductive outcomes of EHV-1 abortion epizootics in unvaccinated Thoroughbred mares in South Africa. Equine veterinary journal, 47(2), 155–159. DOI: 10.1111/evj.12264
Sloet van Oldruitenborgh-Oosterbaan, M. M., Schipper, F. C., Goehring, L. S., & Gremmels, J. F. (1999). Rhinopneumonie of mycotoxine-intoxicatie? Neurologische verschijnselen bij paarden op een manege [Rhinopneumonia or mycotoxin intoxication? Neurologic phenomena in horses from a riding school]. Tijdschrift voor diergeneeskunde, 124(22), 679–681.
Stasiak, K., Dunowska, M., & Rola, J. (2018). Prevalence and sequence analysis of equid herpesviruses from the respiratory tract of Polish horses. Virology journal, 15(1), 106. DOI: 10.1186/s12985-018-1018-3
Stasiak, K., Dunowska, M., Hills, S. F., & Rola, J. (2017). Genetic characterization of equid herpesvirus type 1 from cases of abortion in Poland. Archives of virology, 162(8), 2329–2335. DOI: 10.1007/s00705-017-3376-3
Taniguchi, A., Fukushi, H., Matsumura, T., Yanai, T., Masegi, T., & Hirai, K. (2000). Pathogenicity of a new neurotropic equine herpesvirus 9 (gazelle herpesvirus 1) in horses. J. Vet. Med. Sci. 62, 215–218.
Taouji, S., Collobert, C., Gicquel, B., Sailleau, C., Brisseau, N., Moussu, C., Breuil, M. F., Pronost, S., Borchers, K., & Zientara, S. (2002). Detection and isolation of equine herpesviruses 1 and 4 from horses in Normandy: an autopsy study of tissue distribution in relation to vaccination status. Journal of veterinary medicine. B, Infectious diseases and veterinary public health, 49(8), 394–399.DOI: 10.1046/j.1439-0450.2002.00590.x
Tixonova, F., Neustroev, M., Petrova, S., & Baishev, A. (2012). Ispy`tanie e`ffektivnosti vakciny` protiv rinopnevmonii loshadej inaktivirovannoj s immunomodulyatorom v proizvodstvenny`x usloviyax. Veterinarna medicina, 96, 172–174 [in Russian]
Van der Meulen, K. M., Favoreel, H. W., Pensaert, M. B., & Nauwynck, H. J. (2006). Immune escape of equine herpesvirus 1 and other herpesviruses of veterinary importance. Veterinary immunology and immunopathology, 111(1-2), 31–40. DOI:10.1016/j.vetimm.2006.01.006
Wilson, J., & Erickson, D. (1991). Neurological syndrome of rhinopneumonitis. Proc. Am. Coll. Vet. Intern. Med. 9, 419–421.
Yildirim, Y., Yilmaz, V., & Kirmizigul, A. H. (2015). Equine herpes virus type 1 (EHV-1) and 4 (EHV-4) infections in horses and donkeys in northeastern Turkey. Iranian journal of veterinary research, 16(4), 341–344.
Abstract views: 1325 PDF Downloads: 970


